IGA ANTIBODY INDUCED BY IMMUNIZATION WITH PNEUMOCOCCAL POLYSACCHARIDES IS A PROGNOSTIC TOOL IN COMMON VARIABLE IMMUNE DEFICIENCIES

IGA Antibody Induced by Immunization With Pneumococcal Polysaccharides Is a Prognostic Tool in Common Variable Immune Deficiencies

The evaluation of the response to vaccination in patients with inborn errors of immunity is a tool to evaluate T-dependent and T-independent antibody residual function of B lymphocytes and it is part of the diagnostic definition for Common Variable Immune Deficiencies.Currently used classifications for Common Variable Immune Deficiencies patients a

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Generation of heterozygous (MCRIi030-A-1) and homozygous (MCRIi030-A-2) NR2F2/COUP-TFII knockout human iPSC lines

The NR2F2 gene encodes the transcription factor COUP-TFII, which is upregulated in embryonic Handcream mesoderm.Heterozygous variants in NR2F2 cause a spectrum of congenital anomalies including cardiac and gonadal phenotypes.We generated heterozygous (MCRIi030-A-1) and homozygous (MCRIi030-A-2) NR2F2-knockout induced pluripotent stem cell (iPSC) li

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Sub-graph entropy based network approaches for classifying adolescent obsessive-compulsive disorder from resting-state functional MRI

This paper presents a novel approach for classifying obsessive-compulsive disorder (OCD) in adolescents from resting-state fMRI data.Currently, the state-of-the-art for diagnosing OCD in youth involves interviews with adolescent patients and their parents by an experienced clinician, symptom rating scales based on Diagnostic and Statistical Manual

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